Using MRI scans as measures of biological ageing – the Whitehall II (Stress and Health) MRI Substudy’
About the speaker
University of Oxford Professor of Old Age Psychiatry. Graduated in Medicine from the University of Bonn (1981), trained in Psychiatry in Aberdeen and worked as Lecturer in Mental Health (Aberdeen), MRC Scientist and Chair of Psychiatry (Edinburgh) until 2006, and then Foundation Chair of Old Age Psychiatry (Oxford). Interested in imaging large samples of participants to isolate the effects of healthy and pathological brain ageing. Particular interest in brain mechanisms that protect against psychiatric illness, such as depression and dementia.
We have teamed up with the Whitehall II Study at UCL and the Oxford Centre for Functional MRI of the Brain (FMRIB) to examine 800 volunteers, who have been followed up 2-yearly for the last 30 years. Whitehall Imaging Oxford is participant in the EU Horizon 2020 Project Lifebrain. Our focus of interest is on the interaction of genetic, environmental, social, and psychological factors that confer risk and resilience on people as they age. Our imaging, cognitive and psychiatric research aims to investigate emerging evidence of the brain architecture that enables individuals to compensate cognitively and emotionally, particularly with advancing age.
I will give short introduction to Whitehall II Imaging and Lifebrain, report on preliminary results that link secondary stress markers in mid-life to brain structure and function around 70 years, and specifically describe predictors of resilience to age-related brain damage and the brain effects of moderate wine consumption.
This event is part of a seminar series:
Trinity Term 2017 Seminar Series ‘Ageing, Wellbeing and Health’ Thursdays at 14:00 – 15:30 Seminar Room: 66 Banbury Road, Oxford OX2 6PR Convener: Dr Sara Zella This seminar series will be a fascinating journey between theories and concepts of ageing, health and well-being. The talks will underline the mechanisms behind a happy, healthy and long life, ...
25 May 2017 14:00 - 15:30
Oxford Institute of Population Ageing
66 Banbury Road, Oxford, OX2 6PR